Cura heat up to 24h back ampamp shoulder pain relief with penetrating heat action lasts for 12 hour and once removed the pain relief can continue for a further 12 hours resulting in up to 24 hours pain relief just open the sachet and apply to clothingunderwear where the heat radiates through to the source of pain increasing circulation decreasing stiffness and relaxing sore muscles fragrance free non medicinal and with a thin discreet design they are ideal to use anywhere