Colofac ibs irritable bowel syndrome tablets are a well known antispasmodic meaning they help the bowel to relax making movement of stools more normal it contains the active ingredient mebeverine hydrochloride which is used for the management of irritable bowel syndrome colofac helps relieve the symptoms of ibs which include abdominal pain and cramps bowel spasm diarrhoea and flatulence by relaxing the muscles in the gut colofac helps treat the symptoms of irritable bowel syndrome ch