Nytol one a night tablets are clinically proven to help relieve temporary sleeplessness by promoting a regular sleeping pattern they are the perfect addition to your bedtime routine if youre having trouble drifting off to sleep as you simply take one tablet 20 minutes before bed and youll find no trouble in gaining a full night of rest they work by blocking the normal actions of histamine which is the chemical that stimulates arousal promoting areas of the brain in order to reduce alertnes