Neostrata renewal cream 30g 12 pha 100 of respondents had improvement in the appearance of fine lines wrinkles and skin clarity in 12 weeks of using this gluconolactone pro retinol vitamin e blend 8226visibly reduces fine lines and wrinkles 8226improves sun damage and evens pigmentation 8226formulated with 12 gluconolactone pro retinol and vitamin e 8226due to the vitamin a derivate this product is not recommended for sensitive skin