What is mesotherapy mesotherapy is a non invasive technique based on superficial microinjections just below the epidermis into the target tissues the term meso is derived from the mesoderm or middle layer of the skin approx 1 mm deep mesotherapy is a treatment that stimulates the mesoderm which relieves a wide variety of symptoms and ailments the solution injected can contain a wide range of minerals vitamins amino acids nucleic acids and co enzymes that can be tailored to each p