Visit the mercure manchester piccadilly hotel for a vibrant hotel overlooking the city centre the hotels recent 18 million refurbishment programme has carefully transformed this manchester icon back to its rightful position as a quality 4 star hotel in the north west the mercure manchester piccadilly is a completely non smoking hotel and is an ideal city centre location easily accessible from the m6 and m60 all 280 bedrooms have a bright contemporary style and feature flat screen lcd tvs