An effective solution to wrinkles uneven skin tone and dark spotsla roche posay has developed redermic r with 03 retinol redermic r has clinically tested anti wrinkle efficacy it helps to reduce the appearance of wrinkles and dark spots and is suitable for sensitive skin contains 03 retinol exclusive retinol booster complex retinol linoleate adenosine lipo hydroxy acid lha 03directions of useapply in the evening on face and neck alone or in combination with a moisturis