Loctite threadlockers loctite 1295164 loctite 2400 is a medium threadlocker formulated to secure and seal bolts nuts and studs to prevent loosening due to vibration it works on all metals and passive substrates slight contamination by industrial oils corrosion prevention oils and cutting fluids is tolerated loctite 2400s key differentiator is the white material safety data sheet it carries no hazard symbols risk or safety phrases and does not contain any declarable carcinogens muta