Methylsulphonylmethane msm is a naturally occurring source of sulphur one of the major building blocks of glycosaminoglycans vitamin c is involved in collagen formation manganese plays a role in the maintenance of normal bone and in the normal formation of connective tissue ginger and white willow provide additional natural herbal support to this unique formulation methylsulphonylmethane msm is a naturally occurring source of sulphur one of the major building blocks of glycosaminoglyca