History in the heart of the south welcome to the hampton inn suites grenada located along the yalobush river in northwest mississippi grenada is a historic small town with classic southern charm if youre looking for a hotel in grenada the hampton inn suites hotel is close to everything nearby grenada lake offers many choices for those that enjoy the peace and serenity of nature take your pick from short long or even intermediate length trails no matter which way you wander youl