Your gateway to st louis welcome to the hampton inn st louiscolumbia il in the shadow of st louis gateway arch on the banks of the mighty mississippi river youll find the quiet suburban community of columbia illinois our hotel in columbia is conveniently located adjacent to i 255 less than 15 miles from downtown st louis and southern st louis county is just over the river and just minutes away from our hotel columbias small town midwestern charm provides a perfect retreat for