Discover a pearl of a town welcome to the hampton inn muscatine ia muscatine iowa is a charming community nestled on the picturesque banks of the mississippi river famous for being the largest fresh water pearl button manufacturing center in the world its prosperous past has left a legacy of gorgeous buildings built in a variety of styles all sharing a view of the verdant river area the area surrounding the hampton inn muscatine hotel boasts thousands of acres of native forests and wetla