E45 cream pump has been clinically proven to treat and soothe dry itching flaking chapped rough and calloused skin sunburn and detergent damaged hands e45 cream is a non greasy emollient formulation which is quickly absorbed and leaves your skin soft comfortable and relieved e45 cream can also be used for more serious dry skin conditions such as eczema dermatitis ichthyosis and certain dry cases of psoriasis e45 works by replacing lost moisture and forms a protective barrier e4