E45 cream has been clinically proven to treat and soothe dry itching flaking chapped rough and calloused skin sunburn and detergent hands treatment for dry skin conditions effective and pleasant to use its non greasy emollient formulation is quickly absorbed by your skin leaving it soft comfortable and relieved e45 cream is recommended for more serious dry skin conditions such as eczema dermatitis ichthyosis and certain dry cases of psoriasise45 cream can be used everyday by the wh