Panadol extra soluble tablets are used to relieve the most febrile conditions such as headache migraine backache toothache colds and influenza sore throat rheumatic pain and period pain panadol extra soluble tablets contain two active ingredients paracetamol and caffeine the paracetamol is a pain reliever that will help to reduce temperature during a fever and the caffeine helps to further amplify the pain relieving properties of paracetamol the soluble format means that the tablets can