Did you know what are the four main biochemical triggers that contribute to acne 1 chronic stress 2 overactive sebaceous glands 3 dead skin cell accumulation 4 bacteria and inflammation what can be done to help treat and prevent adult acne inhibiting the activity of overactive sebaceous glands stimulate the natural exfoliation controlling bacteria and fatty acids that contribute to irritation application of topical anti inflammatory dermalogica medibac clearing system and o