B on 1 patches support the bodys natural ability to process alcohol it works with your bodys natural defence systems by providing thiamin vitamin b1 which your body needs to cope with alcohol consumption simply apply the patch topically to the skin preferably in an area with little to no body hair if drinking alcohol apply the patch 30 minutes before consuming for best results the patch contains 75 milligrams of thiamin better known as vitamin b1 leave it on for the next 24 hours v