Premique 0315mg modified release tablets belong to a group of medicines known as hormone replacement therapy hrt it is used to treat some of the symptoms and conditions associated with the menopause premique low dose 003mg15mg modified release tablets is a period free hrt an hrt product where you do not have a monthly bleed your periods will stop once menopause is reached this change is due to lowered levels of the normones estrogen and progesterone you may experience a numbe