A vogel bio propolis cold sore barrier ointment 2g a clinically proven cold sore treatment made from purified propolis extract from canadian popular trees it contains a specific spectrum of active ingredients termed acf active complex of flavonoids propolis has been used as a medicine for more than 2000 years it consists of the plant exudates that honeybees collect and take to the hive where other bees mix them with beeswax to make an antiseptic sealant for the crevices in the hive p